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Updated: May 12, 2026

08:05
A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery
Published on: November 8, 2019
[Interventional angioradiology as a solution for microsurgical flap failure].
E Coeugniet1, P G Harris, G Soulez
1Service de chirurgie plastique, CHUM, Hôtel-Dieu de Montréal, 3840 rue Saint-Urbain, Montréal, Québec, Canada. e_coeugniet@hotmail.com
Summary
Microsurgical free flap salvage can be improved using interventional radiology techniques like thrombolysis and stenting. Angiography can reveal salvage options, potentially reducing flap loss and improving long-term outcomes.
Area of Science:
- Interventional Radiology
- Microsurgery
- Vascular Surgery
Background:
- The failure rate of microsurgical free flaps has remained stagnant for decades, posing a significant challenge in reconstructive surgery.
- Conventional flap revision techniques are not always successful in salvaging compromised free flaps.
Observation:
- Two case reports detail novel angioradiological salvage methods for free flaps where initial revisions failed.
- The first case demonstrated successful in situ thrombolysis to restore blood flow.
- The second case highlighted the pioneering use of stents in a microsurgical anastomosis to maintain patency.
Findings:
- Angioradiological interventions, including thrombolysis and stenting of anastomoses, offer viable rescue strategies for failing free flaps.
- These techniques were effective in salvaging flaps that would have otherwise been deemed unsalvageable.
Implications:
- Pre-abandonment angiography should be considered to identify potential angioradiological salvage options for free flaps.
- Implementing these interventional radiology techniques could significantly improve the long-term success rates of microsurgical free flaps.