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A Faster, High Resolution, mtPA-GFP-based Mitochondrial Fusion Assay Acquiring Kinetic Data of Multiple Cells in Parallel Using Confocal Microscopy
Published on: July 20, 2012
Aggregation-induced emission of a novel conjugated phosphonium salt and its application in mitochondrial imaging
Wen-dan Chen1, Da-wei Zhang, Wei-tao Gong
1School of Chemical Engineering, Dalian University of Technology, No. 2 Ling Gong Road, High Technology Zone, Dalian 116024, PR China.
Abstract:
A new conjugated phosphonium salt TPP was synthesized readily from phosphine-triggered ring-opening of 2,4,5-triphenylpyrylium salt. In aqueous solution, it exhibited interesting AIEE properties and self-assembled into fluorescent nanoparticles, which can be used as a fluorescence probe to image mitochondria in cells.

