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Using a Pan-Viral Microarray Assay (Virochip) to Screen Clinical Samples for Viral Pathogens

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Viral surveillance and discovery.

Walter Ian Lipkin¹, Cadhla Firth

¹Center for Infection and Immunity, Mailman School of Public Health of Columbia University, 722 West 168th Street, New York, NY 10025, USA. wil2001@columbia.edu

Current Opinion in Virology

|April 23, 2013

Summary

Advancements in high-throughput sequencing and global surveillance accelerate virus discovery, linking novel agents to both acute and chronic diseases for improved public health.

Area of Science:

Virology
Microbial Genomics
Public Health

Background:

High-throughput sequencing and bioinformatics have revolutionized virus discovery.
Global microbial surveillance efforts now encompass diverse hosts and diseases.
Viruses are increasingly recognized in chronic disease etiologies.

Purpose of the Study:

To review current methods in viral surveillance and discovery.
To examine strategies and challenges in associating viral discoveries with disease.
To identify future opportunities for advancing viral research and public health.

Main Methods:

Review of existing literature on viral surveillance and discovery techniques.
Analysis of bioinformatics tools for viral identification and characterization.

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Last Updated: May 12, 2026

Using a Pan-Viral Microarray Assay (Virochip) to Screen Clinical Samples for Viral Pathogens

Using a Pan-Viral Microarray Assay (Virochip) to Screen Clinical Samples for Viral Pathogens

Published on: April 27, 2011

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors

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Published on: September 13, 2018

Unbiased Deep Sequencing of RNA Viruses from Clinical Samples

Unbiased Deep Sequencing of RNA Viruses from Clinical Samples

Published on: July 2, 2016

Discussion of global surveillance network strategies and their limitations.

Main Results:

High-throughput sequencing enables rapid identification of known and novel viruses.
Global surveillance investments enhance detection of viral agents in various hosts.
Linking viral discoveries to disease causation presents significant strategic and technical challenges.

Conclusions:

Improvements in sequencing technology and data analysis are crucial.
Integrating social media and medical informatics can enhance viral detection and understanding.
Advancing viral discovery and surveillance is vital for clinical medicine and public health.