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Updated: May 12, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
Published on: July 18, 2025
Acute renal failure caused by bilateral ureteral herniation through the sciatic foramen
James J Whyburn1, Ahmadreza Alizadeh
1Department of Radiology, Lenox Hill Hospital, New York, NY 10075, USA. jwhyburn@nshs.edu
Bilateral ureterosciatic herniation is a rare condition causing kidney damage. Surgical repair, including ureteral stent placement and laparoscopic surgery, effectively treated the condition and restored renal function.
Area of Science:
- Urology
- Surgical Innovation
- Medical Imaging
Background:
- Ureteral herniation, particularly bilateral ureterosciatic herniation, is an exceptionally rare clinical presentation.
- This condition can lead to significant renal complications, including hydronephrosis and acute renal failure, necessitating prompt diagnosis and management.
Observation:
- A 74-year-old female presented with flank pain and acute renal failure, initially detected via ultrasound showing bilateral hydronephrosis.
- Computed tomography (CT) confirmed bilateral ureterosciatic herniation as the cause of obstruction and subsequent renal damage.
- Initial treatment with bilateral retrograde ureterography and ureteral stent placement temporarily improved renal function, but herniation recurred upon stent removal.
Findings:
- Laparoscopic bilateral ureterolysis combined with sciatic notch hernia repair using mesh provided a definitive solution.
- The surgical intervention successfully addressed the ureteral obstruction and resolved the recurrent herniation.
- Post-operative recovery was marked by normalization of renal function, indicating the efficacy of the definitive surgical approach.
Implications:
- This case highlights the importance of advanced imaging in diagnosing rare urological conditions like bilateral ureterosciatic herniation.
- It underscores the potential for recurrence after conservative management and the necessity for definitive surgical correction.
- Laparoscopic techniques offer a minimally invasive and effective option for treating complex ureteral herniations and associated hernias.
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