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Updated: May 12, 2026

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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Conformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective

Anita M Preininger1, Jens Meiler, Heidi E Hamm

  • 1Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232-6600, USA. Anita.Preininger@vanderbilt.edu

Journal of Molecular Biology
|April 23, 2013
PubMed
Summary

Investigating G protein-coupled receptor dynamics reveals key conformational changes during activation. Combining computational and experimental methods enhances understanding of these complex molecular interactions.

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