Related Experiment Video
Updated: May 12, 2026

11:20
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Microincision vitrectomy surgery for myopic foveoschisis
Jong Uk Hwang1, Soo Geun Joe, Joo Yong Lee
1Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
The British Journal of Ophthalmology
|April 23, 2013
Summary
Microincision vitrectomy surgery (MIVS) with internal limiting membrane (ILM) peeling is a feasible and effective treatment for myopic foveoschisis (MF). This procedure significantly improves visual acuity and resolves anatomical abnormalities in highly myopic eyes.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Microsurgery
Background:
- Myopic foveoschisis (MF) is a degenerative condition affecting the macula in highly myopic eyes.
- Surgical intervention is often necessary to address MF and prevent vision loss.
Purpose of the Study:
- To assess the technical feasibility of microincision vitrectomy surgery (MIVS) for MF.
- To evaluate the surgical outcomes, including visual acuity and anatomical restoration, following MIVS in patients with MF.
Main Methods:
- A cohort of 29 patients (33 eyes) with MF diagnosed via spectral-domain optical coherence tomography (SD-OCT) underwent MIVS.
- The surgical procedure involved internal limiting membrane (ILM) peeling, with or without intraocular gas tamponade.
- Postoperative follow-up included best-corrected visual acuity (BCVA) assessment and SD-OCT imaging for 6 months.
Main Results:
- Mean BCVA improved significantly from 1.01 to 0.76 logMAR (p=0.004).
- Central subfield thickness decreased from 431 μm to 231 μm (p<0.001).
- Complete MF resolution and foveal reattachment were achieved in 96% of cases; macular holes closed in all four instances.
Conclusions:
- MIVS with ILM peeling demonstrates favorable visual and anatomical outcomes in highly myopic eyes with MF.
- The technique is technically feasible and offers a promising surgical option for managing this condition.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...

