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06:32
Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
Published on: November 4, 2022
Prostate cancer research in China
Shan-Cheng Ren1, Rui Chen, Ying-Hao Sun
1Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
Asian Journal of Andrology
|April 23, 2013
Summary
Recent prostate cancer (PCa) research in China shows significant advancements. Studies include genome-wide association studies (GWAS) identifying new risk SNPs and next-generation sequencing revealing novel genetic variations for PCa.
Area of Science:
- Oncology
- Genetics
- Genomics
Background:
- Prostate cancer (PCa) research in China is rapidly advancing.
- Significant progress has been made in understanding PCa genetics and progression.
Purpose of the Study:
- To review recent progress in prostate cancer research in China.
- To highlight potential future breakthroughs in PCa research and treatment.
Main Methods:
- Genome-wide association studies (GWAS) to identify PCa risk-associated single nucleotide polymorphisms (SNPs).
- Next-generation sequencing (NGS) to detect gene fusions, long non-coding RNAs, and other variations.
- Investigation of PCa progression mechanisms and diagnostic biomarkers.
Main Results:
- Identification of two novel PCa risk-associated SNPs in the Chinese population through GWAS.
- Discovery of gene fusions, long non-coding RNAs, and other genetic variations using NGS.
- Elucidation of PCa progression mechanisms and extensive investigation of diagnostic biomarkers.
Conclusions:
- Personalized therapies, including those based on genetic factors, nano-medicine, and traditional Chinese medicine, are a focus of experimental PCa therapeutics.
- Recent advancements in PCa research in China are paving the way for future breakthroughs in diagnosis and treatment.
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