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Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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Updated: May 12, 2026

RNAi-mediated Control of Aflatoxins in Peanut: Method to Analyze Mycotoxin Production and Transgene Expression in the Peanut/Aspergillus Pathosystem
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[25 years Mycotoxin workshop].

M Gareis1

  • 1Institut für Mikrobiologie und Toxikologie an der Bundesanstalt für Fleischfor-schung (BAFF), E.-C. Baumannstr. 20, D-95326, Kulmbach, Germany.

Mycotoxin Research
|April 23, 2013
PubMed
Summary
This summary is machine-generated.

This review traces the 25-year history of German Mycotoxin-Workshops, highlighting their evolution from federal research gatherings to an internationally recognized society promoting mycotoxin research and education.

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Area of Science:

  • Mycotoxicology
  • Food Safety
  • Veterinary Toxicology

Context:

  • Mycotoxin research in Germany has a 25-year history, marked by annual workshops.
  • Initial workshops focused on food/feed safety, mycology, and mycotoxin analysis/toxicology.
  • The scope expanded to include universities, international scientists, and diverse disciplines.

Purpose:

  • To provide a historical overview of the Mycotoxin-Workshops in Germany.
  • To document the growth and evolution of the mycotoxin research community.
  • To highlight the role of the Society for Mycotoxin Research in organizing events and promoting research.

Summary:

  • The first Mycotoxin Workshop in 1979 brought together federal scientists to discuss food safety, mycology, and toxicology.
  • Over 25 years, workshops grew to over 150 participants from various institutions and countries.
  • The Society for Mycotoxin Research, founded in 1997, now organizes these workshops and supports research through awards and fellowships.

Impact:

  • Established a long-standing tradition of scientific exchange in mycotoxicology.
  • Fostered interdisciplinary collaboration and international participation in mycotoxin research.
  • Promotes the advancement of mycotoxin knowledge through organized events and research support.