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Updated: May 12, 2026
Natural Product Discovery with LC-MS/MS Diagnostic Fragmentation Filtering: Application for Microcystin Analysis
Published on: May 31, 2019
Determination of macrocyclic trichothecenes in mouldy indoor materials by LC-MS/MS
C Gottschalk1, J Bauer, K Meyer
1Chair of Animal Hygiene, TU München, Weihenstephaner Berg 3, 85354, Freising, Germany, christoph.gottschalk@wzw.tum.de.
Abstract:
Stachybotrys occurring in mouldy indoor environments is associated with the so called "sick building syndrome" in humans or cases of idiopathic pulmonary hemorrhages. Samples of mouldy materials from indoor environments (n=15) were analysed for the occurrence of this fungus and its secondary metabolites by a sensitive LC-MS/MS method. In four samples,Stachybotrys and macrocyclic trichothecenes have been detected. Maximum values for Satratoxin G and H in wallpaper were determined with 9.7 μg/cm(2) and 12.0 μg/cm(2), respectively.
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