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Cholecystitis

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Updated: May 12, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Published on: February 10, 2015

Streptococcus bovis-related cholecystitis.

Eoin McCarthy Deering¹, Zlatko Muravec, Constantino Fiuza Castineira

¹Department of Surgery, South Eastern Cancer Centre, Waterford, Ireland.

BMJ Case Reports

|April 23, 2013

Summary

Acute cholecystitis is typically caused by common bacteria. This report details a rare case of gallbladder inflammation caused by Streptococcus bovis, a bacterium usually found in the digestive system.

Area of Science:

Gastroenterology
Microbiology

Background:

Acute cholecystitis is a frequent gallbladder inflammation, predominantly caused by Escherichia coli, Enterococcus, and Klebsiella.
Streptococcus bovis is a Gram-positive anaerobic coccus residing commensally in the digestive tract of 16% of healthy individuals.

Observation:

This study presents a rare instance of acute cholecystitis attributed to Streptococcus bovis infection.

Findings:

The causative agent, Streptococcus bovis, is identified as a Gram-positive, catalase-negative anaerobic coccus.
This bacterium is a known commensal organism within the human digestive system.

Implications:

This case highlights the potential for Streptococcus bovis to cause acute cholecystitis, a condition not commonly associated with this pathogen.

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The findings warrant further investigation into the pathogenic potential of Streptococcus bovis, particularly concerning its two biotypes (I and II), and their links to various gastrointestinal diseases.