Related Experiment Video
Updated: May 12, 2026

Human Egg Maturity Assessment and Its Clinical Application
Published on: August 19, 2019
Stable expressions of nine genes within human oocytes and live birth by in vitro fertilisation
Hisashi Moriguchi1, Joren Madson
1Reprogramming Inc, Chiba, Japan. moriguchi-tky@umin.ac.jp
Abstract:
The development of new methods to cryopreserve human ovarian cortex tissues without damage is needed for the improvement of quality of life of female cancer patients. Here, we show that stable expressions of nine genes within human oocytes by using a supercooling procedure are necessary in order to produce human mature eggs and experience live births with high safety profiles by in vitro fertilisation. Our method will be helpful in order to preserve the fertility of female cancer patients or healthy women.
Related Concept Videos
Oogenesis
Oogenesis
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Fertilization
In Vitro Fertilization
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

