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Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

Cholecystitis

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.

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Related Experiment Video

Updated: May 12, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025

Subhepatic appendicitis: a diagnostic dilemma.

William Robert Ball¹, Antonio Privitera

¹Department of Surgery, University Hospital North Staffordshire, Stoke-on-Trent, UK. ballwilliam@doctors.org.uk

BMJ Case Reports

|April 23, 2013

Summary

This summary is machine-generated.

A woman experienced persistent abdominal pain after gallbladder removal. Doctors discovered an inflamed appendix in an unusual location, requiring surgery and leading to a full recovery.

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Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

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Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

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Published on: March 10, 2023

Area of Science:

Gastroenterology
Surgical Pathology

Background:

Recurrent abdominal pain can present diagnostic challenges, especially post-cholecystectomy.
Unusual presentations of common conditions like appendicitis can mimic other pathologies.

Observation:

Despite cholecystectomy, the patient experienced persistent, worsening abdominal pain, leading to readmission.
Elevated inflammatory markers and ultrasound revealed a tubular hypoechoic structure in the subhepatic region.

Findings:

Diagnostic laparoscopy identified an inflammatory mass of appendicular origin in the subhepatic space.
The mass necessitated a right colon mobilization and appendicectomy.
Histological examination confirmed acute appendicitis with mucosal ulceration.

Implications:

This case highlights appendicitis as a rare but significant cause of post-cholecystectomy abdominal pain.
It underscores the importance of considering atypical diagnoses in persistent post-operative symptoms.
Accurate diagnosis and surgical management are crucial for resolving such complex presentations.