In vitro studies on the evaluation of mycotoxin decontaminating agents

The ability of 6 commercially available decontaminating agents and cholestyramine to adsorb deoxynivalenol and zearalenone was testedin vitro. All of the products showed poor adsorbtion abilities for deoxynivalenol. For zearalenone adsorbtion great differences were found between the tested products. Using the Langmuir equation the amount of adsorbing agent necessary for a 50% binding of zearalenone, assuming a diet containing 1mg/kg zearalenone, could be estimated for cholestyramine at 0.1 kg/t feedstuff, for Toxisorb® at 1.2 kg/t and for Mykosorb® Extra at 7.6 kg/t underin vitro conditions. The results need to be verifiedin vivo.