Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Selective termination: clinical experience and residual risks.

M I Evans1, M May, A Drugan

  • 1Division of Reproductive Genetics, Hutzel Hospital-Wayne State University, Detroit, MI 48201.

American Journal of Obstetrics and Gynecology
|June 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Study of the problem of balneo-physiotherapy of rheumatism].

Probleme de reumatologie·2014
Same author

Cases of Delirium Tremens Rapidly Cured by Hydrate of Chloral.

British medical journal·2010
Same author

The effects of meperidine and epidural analgesia in labor on maternal heart rate variability.

International journal of obstetric anesthesia·2009
Same author

The CLE family of plant polypeptide signaling molecules.

Cellular and molecular life sciences : CMLS·2007
Same author

Placental TFPI is decreased in gestational vascular complications and can be restored by maternal enoxaparin treatment.

Journal of thrombosis and haemostasis : JTH·2005
Same author

Sonographic nuchal markers for Down syndrome are more common but less ominous in gestations with a male fetus.

Fetal diagnosis and therapy·2002
Same journal

Trends in Infertility Treatments by Race, Ethnicity, Socioeconomic Status, and Region in U.S. Birth Certificates from Live Births: 2011-2022.

American journal of obstetrics and gynecology·2026
Same journal

Likelihood ratios enhance clinical interpretation of metagenomic prediction of early-onset neonatal sepsis in preterm premature rupture of membranes (Letter-to-the-Editor).

American journal of obstetrics and gynecology·2026
Same journal

Taking risk stratification in preterm premature rupture of membranes to the bedside (Reply to Letter-to-the-Editor).

American journal of obstetrics and gynecology·2026
Same journal

Gestational Age at Full-Term Delivery and Long-Term Offspring Morbidity in Low-Risk Pregnancies: A Population-Based Cohort Study.

American journal of obstetrics and gynecology·2026
Same journal

Trajectories of childbirth-related posttraumatic stress symptoms after a vaginal delivery: a multicenter prospective study.

American journal of obstetrics and gynecology·2026
Same journal

Early life adversity and polycystic ovary syndrome among North American pregnancy planners.

American journal of obstetrics and gynecology·2026
See all related articles

Selective termination procedures in multifetal pregnancies improve intact survival rates. The study supports optimally leaving twins, balancing procedure risks against obstetric complications.

Area of Science:

  • Reproductive Medicine
  • Maternal-Fetal Medicine
  • Medical Ethics

Background:

  • Assisted reproductive technologies (ART) can lead to multifetal pregnancies, posing risks to maternal and fetal health.
  • Selective termination is a procedure to reduce the number of fetuses in multifetal gestations to improve outcomes.
  • Ethical considerations and balancing risks are crucial in managing multifetal pregnancies resulting from ART.

Purpose of the Study:

  • To evaluate the success and outcomes of transabdominal first-trimester selective termination procedures.
  • To determine the optimal number of fetuses to retain in multifetal gestations.
  • To weigh the risks of selective termination against the risks of continuing a high-order multifetal pregnancy.

Main Methods:

  • Performed transabdominal selective termination in 22 multifetal pregnancies (octuplets to quadruplets).
Keywords:
DetroitGenetics and ReproductionHutzel Hospital/Wayne State University (Detroit, MI)

Related Experiment Videos

  • Monitored pregnancy outcomes, including intact survival, deliveries, ongoing pregnancies, and losses.
  • Counseled patients on procedure success likelihood and potential late losses.

    • Main Results:

    • Successful transabdominal selective termination was achieved in the studied multifetal gestations.
    • Outcomes included 8 sets of twins and 2 singletons delivered, with 7 twin pregnancies ongoing.
    • One early and four late pregnancy losses were observed, highlighting concerns for late-term complications.

    Conclusions:

    • Selective termination is a viable option for managing high-order multifetal pregnancies, aiming to increase intact survival.
    • While technically successful, late pregnancy losses remain a concern, necessitating careful patient counseling.
    • The current protocol supports optimally leaving twins, based on obstetric risks and ethical considerations, though the ideal number requires further study.