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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Ascites01:19

Ascites

DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...

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Updated: May 12, 2026

Acupoint Catgut Embedding Therapy for Abdominal Obesity Treatment
05:18

Acupoint Catgut Embedding Therapy for Abdominal Obesity Treatment

Published on: November 22, 2024

Obesity-associated abdominal elephantiasis.

Ritesh Kohli1, Vivian Argento, Yaw Amoateng-Adjepong

  • 1Department of Internal Medicine, Bridgeport Hospital, Yale University School of Medicine, Columbia Tower, Appt. no. 308, 50 Ridgefield Avenue, Bridgeport, CT 06610, USA.

Case Reports in Medicine
|April 23, 2013
PubMed
Summary

Abdominal elephantiasis, a rare skin condition causing leg and abdominal swelling, requires early diagnosis. Prompt treatment is crucial for managing this progressive disease and preventing complications.

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An Acupoint Catgut-embedding Therapy for Treating Obesity
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Last Updated: May 12, 2026

Acupoint Catgut Embedding Therapy for Abdominal Obesity Treatment
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Acupoint Catgut Embedding Therapy for Abdominal Obesity Treatment

Published on: November 22, 2024

An Acupoint Catgut-embedding Therapy for Treating Obesity
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Published on: April 4, 2025

Area of Science:

  • Dermatology
  • Infectious Diseases

Background:

  • Abdominal elephantiasis is a rare, progressive cutaneous disease.
  • It results from chronic lymphedema and recurrent bacterial infections of the abdominal wall.
  • Morbid obesity is a potential contributing factor.

Purpose of the Study:

  • To present three cases of abdominal elephantiasis in morbidly obese patients.
  • To highlight the clinical presentation and management challenges.

Main Methods:

  • Case series presentation of three patients with abdominal elephantiasis.
  • Clinical examination, patient history, and treatment outcomes were documented.

Main Results:

  • Patients presented with abdominal and leg edema, thickened skin plaques, erythema, and pain.
  • Two patients had localized skin erythema, tenderness, and warmth.
  • One patient exhibited purulent drainage; initial antibiotic treatment showed limited improvement.

Conclusions:

  • Early diagnosis of abdominal elephantiasis is critical for effective treatment.
  • Prompt intervention is necessary to prevent disease progression and complications.