Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bacterial Meningitis I: Introduction

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...

Bacterial Meningitis II: Pathophysiology

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...

Viral Meningitis

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

Brain Abscess l: Introduction

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

Cranial and Spinal Meninges

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...

Encephalitis l: Introduction

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Letter to the Editor Regarding "Creating a Comprehensive Research Platform for Surgical Technique and Operative Outcome in Primary Brain Tumor Neurosurgery".

World neurosurgery·2020

Same author

Letter to the Editor Regarding 'Stepping Up: How U.S. Neurosurgery Training Programs Can Innovatively Assess Resident Applicants in a Post-Step 1 World'.

World neurosurgery·2020

Same author

Letter to the Editor: Home Program for Acquisition and Maintenance of Microsurgical Skills During the COVID-19 Outbreak.

World neurosurgery·2020

Same author

Letter to the Editor Regarding: "Coronavirus Neurosurgical/Head and Neck Drape to Prevent Aerosolization of Coronavirus Disease 2019 (COVID-19): The Lenox Hill Hospital/Northwell Health Solution".

World neurosurgery·2020

Same author

Letter to the Editor Regarding"Surgical Outcomes of Laser Interstitial Thermal Therapy for Temporal Lobe Epilepsy".

World neurosurgery·2020

Same author

Letter to the Editor Regarding: "Case Volumes and Perioperative COVID-19 Incidence in Neurosurgical Patients During a Pandemic: Experiences at Two Tertiary Care Centers in Washington, DC".

World neurosurgery·2020

Search research articles

Related Experiment Video

Updated: May 12, 2026

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Published on: May 7, 2020

Bilateral multiple level lateral meningocoele.

B E Panil Kumar¹, Kishor V Hegde, G Lalitha Kumari

¹Department of Radio-Diagnosis, Narayana Medical College Hospital, Chinthareddypalem, Nellore, Andhra Pradesh, India.

Journal of Clinical Imaging Science

|April 23, 2013

Summary

Lateral meningocoele, a rare spinal disorder, involves extensions of the dura and arachnoid through enlarged neural foramina. This case highlights multiple bilateral meningocoeles in a young female, managed conservatively.

Keywords:

Lateral meningocele multiple menigocoele spinal dysraphism

More Related Videos

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Published on: February 29, 2020

Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Related Experiment Videos

Last Updated: May 12, 2026

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Published on: May 7, 2020

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Published on: February 29, 2020

Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Area of Science:

Neurosurgery
Radiology
Genetics

Background:

Lateral meningocoele is an exceptionally rare congenital disorder.
It is characterized by extensions of the dura mater and arachnoid mater through enlarged neural foramina.
This condition can be associated with connective tissue disorders and spinal deformities.

Observation:

A 23-year-old female presented with spinal deformity and low back pain.
She had no neurological deficits.
Whole spine magnetic resonance imaging (MRI) was performed.

Findings:

MRI revealed multiple, well-defined, bilateral cystic masses at the dorsal, lumbar, and sacral spinal levels.
Dural ectasia and significant neural foraminal widening were noted.
The findings were consistent with bilateral, multiple-level lateral meningocoele.

Implications:

This case expands the understanding of the varied presentations of lateral meningocoele.
Conservative management with regular follow-up is a viable approach for asymptomatic or minimally symptomatic cases.
Further research into the genetic and developmental factors underlying this rare condition is warranted.