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The Availability Heuristic01:08

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Related Experiment Video

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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

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[Not Available].

Britt-Isabelle Berg1, Nicole Hilber, Konrad Hille

  • 1Klinik für Mund-, Kiefer- und Gesichtschirurgie, Universitätsspital Basel.

Praxis
|April 24, 2013
PubMed
Summary
This summary is machine-generated.

The first Osteo-Odonto-Keratoprosthesis (OOKP) surgery in Switzerland restored vision for a patient with severe corneal impairment. This innovative tooth-and-cornea implant offers a last-resort solution for profound vision loss.

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Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Surgical Innovation

Background:

  • Severe bilateral corneal vision impairment often lacks effective treatment options.
  • Traditional treatments like allogenic corneal transplants may not be suitable for all patients.
  • The Osteo-Odonto-Keratoprosthesis (OOKP) is a complex, multi-stage surgical procedure reserved for end-stage corneal disease.

Purpose of the Study:

  • To report the first successful implantation of an Osteo-Odonto-Keratoprosthesis (OOKP) in Switzerland.
  • To document the surgical technique and outcomes in a patient with severe, untreatable corneal blindness.
  • To highlight OOKP as a viable, albeit complex, reconstructive option.

Main Methods:

  • A two-stage surgical approach was employed, beginning with the removal of a single-rooted tooth and surrounding bone.
  • A tooth-bone-optic-cylinder complex was created and temporarily implanted submuscularly in the infraorbital area.
  • The second stage involved ocular surgery to prepare the eye and implant the OOKP complex, utilizing oral mucosa grafts.

Main Results:

  • The patient achieved a best-corrected visual acuity of 0.7 (approximately 20/28) after the OOKP implantation.
  • The procedure successfully restored functional vision in a case of severe bilateral corneal pathology.
  • The complex surgical technique, involving dental and ocular components, was successfully executed.

Conclusions:

  • The Osteo-Odonto-Keratoprosthesis (OOKP) is a feasible and effective treatment for severe bilateral corneal vision impairment in Switzerland.
  • This advanced prosthetic offers a significant visual rehabilitation option when conventional methods fail.
  • Further research and case studies are warranted to establish long-term outcomes and refine the OOKP procedure.