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Burden of respiratory tract infections among paediatric in and out-patient units during 2010-11

J Mazumdar1, M Chawla-Sarkar, K Rajendran

  • 1Division of Virology and Division of Data Management, National Institute of Cholera and Enteric Diseases (NICED), Beliaghata, Kolkata, West Bengal, India. jaymaz28@gmail.com

European Review for Medical and Pharmacological Sciences
|April 24, 2013
PubMed

Insights

Viral respiratory infections were more common in hospital outdoor units. Influenza B virus (IBV) predominated outdoors, while respiratory syncytial virus (RSV) was more frequent indoors, particularly in young children.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Epidemiology

Background:

  • Viral respiratory tract infections (RTIs) are a significant public health concern.
  • Understanding pathogen distribution in different hospital settings is crucial for infection control.

Purpose of the Study:

  • To identify and compare viral pathogens causing RTIs in hospital indoor versus outdoor units.
  • To analyze the prevalence of specific viruses in relation to patient location and age.

Main Methods:

  • A hospital-based cross-sectional study involving 880 children under 12 years.
  • Real-time RT-PCR screening of throat and nasal swabs from indoor and outdoor units.
  • Multinomial logistic regression analysis to identify risk factors.

Main Results:

  • Overall viral positivity rates were 30% in outdoor and 25% in indoor units.
  • Influenza B virus (IBV) was more prevalent in outdoor units (16%), while respiratory syncytial virus (RSV) was more common in indoor units (16%).
  • RSV and Influenza viruses were predominant in children under 5 years; pandemic influenza A (pH1N1/2009) was more frequent in outdoor settings.

Conclusions:

  • Hospital outdoor departments had higher patient attendance and viral infection rates compared to indoor units.
  • Continuous surveillance and effective vaccination programs are recommended for managing viral RTIs.
  • Age is a significant factor in the prevalence of specific viral respiratory pathogens.
Abstract

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