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Updated: May 12, 2026

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
Published on: May 23, 2025
Surgical anatomy of hand allotransplantation
Brian T Carlsen1, Faisal Al-Mufarrej, Steven L Moran
1Division of Plastic Surgery, Department of Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Abstract:
The hand is the most refined anatomical terminal device known and the leading edge of the sensorium. Further, the hand is second only to the face in terms of visibility and is a vitally important aspect aesthetic and body image. Hand amputation represents a devastating loss of function and independence. Restoring function after limb loss is a challenge and traditionally includes autologous methods and prosthetics. In the last 15 years, hand transplantation has become a viable option for select patients.
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