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Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System

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Diagnostic exercise: poor performance in a racehorse.

F Giannitti¹, R Petrov², J Parker²

¹California Animal Health and Food Safety (CAHFS) Laboratory System, School of Veterinary Medicine, University of California, Davis, CA, USA fgiannitti@ucdavis.edu.

Veterinary Pathology

|April 24, 2013

Summary

This summary is machine-generated.

This study details a case of a Thoroughbred gelding with prolonged poor performance and fever, ultimately diagnosed with severe liver disease. Diagnostic findings highlight significant hepatomegaly and fibrosis, underscoring the challenges in equine liver pathology.

Keywords:

Avena fatua (wild oat)choledocholithiasis choledochus foreign body horse liver obstruction

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Area of Science:

Veterinary Medicine
Equine Internal Medicine
Hepatology

Background:

A 9-year-old Thoroughbred gelding exhibited a 97-day history of poor performance and intermittent fever.
Clinicopathologic findings included elevated liver enzymes (γ-glutamyltransferase, alkaline phosphatase), mild hyperbilirubinemia, and leukocytosis with neutrophilia and lymphopenia.

Observation:

Abdominal ultrasound revealed hepatomegaly with hyperechoic hepatic parenchyma and biliary distention.
Pathological examination showed marked hepatomegaly (3.6% of body weight), firm consistency, diffuse enhanced reticular pattern, severe portal bridging, sinusoidal fibrosis, oval cell/bile duct hyperplasia, and bile stasis.

Findings:

The case presents a complex equine liver disease with significant histopathological changes.
Diagnostic workup involved clinicopathologic analysis and abdominal ultrasonography to identify the extent of hepatic and biliary abnormalities.

Implications:

This case highlights the diagnostic challenges and pathological features of severe equine liver disease.
Understanding these findings aids in the differential diagnosis and management of similar presentations in horses.