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Updated: May 12, 2026

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Intense pulsed light therapy for aberrant Mongolian spots.

Makiko Shirakawa1, Toshiyuki Ozawa, Chiharu Tateishi

  • 1Department of Dermatology, Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan. m3552667@msic.med.osaka-cu.ac.jp

Osaka City Medical Journal
|April 25, 2013
PubMed
Summary

Intense pulsed light (IPL) effectively treats aberrant Mongolian spots (AMS), showing significant improvement in melanocyte reduction. This study confirms IPL as a viable therapeutic option for these persistent pigmented lesions.

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Area of Science:

  • Dermatology
  • Medical Aesthetics
  • Phototherapy

Background:

  • Aberrant Mongolian spots (AMS) distal to the lumbosacral region often persist longer than typical sacral Mongolian spots.
  • Q-switched ruby laser (QSRL) has been the primary treatment for AMS.
  • Intense pulsed light (IPL) is a versatile light-based therapy with established efficacy for various dermatological conditions.

Purpose of the Study:

  • To evaluate the clinical and histological effectiveness of Intense Pulsed Light (IPL) for treating Aberrant Mongolian Spots (AMS).
  • To compare physician and patient assessments of IPL treatment outcomes for AMS.

Main Methods:

  • Seven pediatric patients (mean age 2.0 years) with AMS were treated using the Natulight IPL device.
  • High-resolution digital photography was used for baseline and 6-month follow-up assessments.

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  • Histopathological analysis, including skin biopsies, was performed on one patient before, immediately after, and 6 months post-treatment.

    • Main Results:

    • Patient families reported excellent improvement in 14%, good in 57%, and slight in 29% of cases.
    • Physician evaluations indicated excellent improvement in 14%, good in 29%, and slight in 57% of cases.
    • Histopathology revealed a significant decrease in melanocytes in the mid and upper dermis 6 months after IPL treatment.

    Conclusions:

    • Intense Pulsed Light (IPL) demonstrates clinical and histological efficacy in treating Aberrant Mongolian Spots (AMS).
    • IPL offers a promising alternative treatment for persistent pigmented lesions like AMS.