Related Experiment Video
Updated: May 12, 2026
07:15
A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
Published on: July 28, 2020
Leiomyosarcoma of the soft palate
Ömer Sağlam1, Samet Vasfi Kuvat, Ümit Taşkın
1Department of Otolaryngology, Kasımpaşa Military Hospital, 34440 Kasımpaşa İstanbul, Turkey.
Summary
This case report details a rare intraoral leiomyosarcoma in a young male patient. The smooth muscle tumor, located on the soft palate, was successfully resected with no recurrence observed over two years.
Area of Science:
- Oral pathology
- Surgical oncology
- Smooth muscle tumors
Background:
- Smooth muscle tumors are uncommon in the oral cavity due to the limited presence of smooth muscle tissue.
- Leiomyosarcoma, a malignant smooth muscle tumor, typically affects the jawbones (maxilla and mandible) when occurring intraorally.
Observation:
- A 20-year-old male presented with a three-month history of a soft palate mass.
- The tumor was situated on the left side of the soft palate.
Findings:
- The soft palate mass was diagnosed as leiomyosarcoma.
- The tumor was completely removed surgically ('en bloc' resection with mucosa).
Implications:
- This case highlights the possibility of leiomyosarcoma occurring in the soft palate, a less common site.
- Successful surgical management and long-term follow-up are crucial for managing oral leiomyosarcomas.
Related Concept Videos
01:03Rous Sarcoma Virus (RSV) and Cancer
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
01:03Rous Sarcoma Virus (RSV) and Cancer
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
01:21Barrett Esophagus-I: Introduction
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
01:27Esophageal Achalasia
Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...