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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...

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Related Experiment Video

Updated: May 12, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

Neuroimaging in frontotemporal dementia.

Jonathan D Rohrer1, Howard J Rosen

  • 1Dementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, UK.

International Review of Psychiatry (Abingdon, England)
|April 25, 2013
PubMed
Summary

Frontotemporal dementia (FTD) involves brain atrophy, affecting behavior or language. Advanced imaging techniques offer new ways to diagnose FTD subtypes and understand its impact on brain networks.

Area of Science:

  • Neurology
  • Neuroimaging

Background:

  • Frontotemporal dementia (FTD) is a group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy.
  • Clinical presentations include behavioral impairments (behavioral variant FTD) or language deficits (primary progressive aphasia - PPA).
  • Existing imaging primarily uses volumetric MRI and PET to detect grey matter changes.

Purpose of the Study:

  • To explore advanced neuroimaging techniques for characterizing FTD subtypes.
  • To investigate the potential of these techniques in differential diagnosis and understanding FTD signatures.

Main Methods:

  • Utilizing diffusion tensor imaging (DTI) to assess white matter tract integrity (structural connectivity).
  • Employing resting-state functional MRI (rs-fMRI) to analyze functional connectivity in resting-state networks.

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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Related Experiment Videos

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Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

  • Applying arterial spin labelling (ASL) perfusion MRI to evaluate brain perfusion.

    • Main Results:

    • Newer imaging methods reveal abnormalities in structural and functional connectivity, as well as perfusion in FTD.
    • These advanced techniques provide more detailed insights compared to traditional volumetric MRI and PET.

    Conclusions:

    • Advanced neuroimaging techniques like DTI, rs-fMRI, and ASL MRI show promise in FTD research.
    • These methods may enhance the differential diagnosis of FTD and offer more specific imaging biomarkers for FTD syndromes.