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Two Hypercard calculators for molecular biology.

¹Department of Biology, Indiana University, Bloomington 47405.

Computer Applications in the Biosciences : CABIOS

|April 1, 1990

Summary

Scientists can create sophisticated calculation tools using Macintosh HyperCard. Two examples, GelFragSizer and Enzyme Kinetics, demonstrate easy-to-use DNA fragment sizing and enzyme kinetics analysis.

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Area of Science:

Biochemistry
Molecular Biology
Scientific Software Development

Background:

Macintosh HyperCard offers a platform for developing custom scientific calculation tools.
There is a need for accessible and user-friendly software for common laboratory calculations.

Purpose of the Study:

To describe two HyperCard stacks, GelFragSizer and Enzyme Kinetics, designed for scientific calculations.
To showcase the capabilities of HyperCard for creating sophisticated yet easy-to-use scientific tools.

Main Methods:

GelFragSizer utilizes local reciprocal or cubic spline methods for estimating and plotting DNA restriction fragment sizes.
Enzyme Kinetics estimates Michaelis-Menton rate parameters for enzyme-catalyzed reactions and visualizes data against estimated curves.

Main Results:

Both GelFragSizer and Enzyme Kinetics provide functional and accessible computational solutions.
The developed stacks demonstrate the practical application of HyperCard in scientific data analysis.

Conclusions:

HyperCard is a viable and powerful tool for scientists to develop custom computational applications.
These examples highlight the potential for creating specialized calculators to aid in research and data interpretation.

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