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Abdominal wall defects: a 33-year unicentric experience

E Guida1, A Pini-Prato, G Mattioli

  • 1Pediatric Surgery Department, Giannina Gaslini Institute, Genoa, Italy. picchiot@libero.it

Minerva Pediatrica
|April 25, 2013
PubMed

Insights

This study reviewed 61 patients with gastroschisis and omphalocele, finding improved survival rates over decades. While most outcomes are good, gastrointestinal and cosmetic issues impact long-term quality of life.

Area of Science:

  • Pediatric Surgery
  • Neonatal Care
  • Congenital Anomalies

Background:

  • Gastroschisis and omphalocele are congenital abdominal wall defects requiring surgical intervention.
  • Long-term outcomes and quality of life for affected patients require ongoing evaluation.

Purpose of the Study:

  • To analyze clinical features, surgical management, and long-term outcomes for gastroschisis and omphalocele patients.
  • To identify factors influencing survival and quality of life in these conditions.

Main Methods:

  • Retrospective review of 61 patients operated on for gastroschisis or omphalocele between 1976 and 2009.
  • Data collected included demographics, maternal history, delivery type, associated anomalies, surgical details, complications, morbidity, and mortality.

Main Results:

  • Survival rates have improved over the study period.
  • Omphalocele patients had more associated anomalies but quicker surgical recovery.
  • Mortality was approximately 5%; long-term follow-up in 18 patients showed satisfactory outcomes despite prevalent gastrointestinal issues (70%).

Conclusions:

  • Gastroschisis and omphalocele management has improved, with no clear advantage of Cesarean section over vaginal delivery.
  • Associated anomalies, particularly cardiac malformations, significantly impact survival.
  • While overall outcomes are positive, gastrointestinal and cosmetic concerns affect patient quality of life.
Abstract

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