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Updated: May 12, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Life-threatening acute disseminated staphylococcal disease in a child
S Ilia1, A M Spanaki, E Mihailidou
1University of Crete, Heraklion, Greece. stayrinah@hotmail.com
Insights
Acute disseminated staphylococcal disease (ADSD) is a severe condition. This case highlights successful treatment of a young child with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection, involving septic shock, osteomyelitis, and deep vein thrombosis.
Area of Science:
- Infectious Diseases
- Pediatric Critical Care
- Staphylococcal Infections
Background:
- Acute disseminated staphylococcal disease (ADSD) is a severe and increasing health concern.
- Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a significant pathogen in ADSD.
- Septic shock, osteomyelitis, and deep vein thrombosis are serious complications.
Observation:
- A two-and-a-half-year-old female presented with CA-MRSA induced septic shock.
- The patient developed concurrent osteomyelitis and deep vein thrombosis.
- This presentation represents an unusual and severe manifestation of ADSD.
Findings:
- Aggressive management was initiated, including long-term antistaphylococcal therapy.
- Anticoagulation and intensive care support were crucial components of the treatment plan.
- The patient achieved complete resolution of disseminated inflammation.
Implications:
- This case underscores the importance of early and aggressive intervention in pediatric ADSD.
- Effective management strategies can lead to favorable outcomes even in complex cases.
- Understanding CA-MRSA's potential for severe disseminated disease is critical for clinicians.
Abstract:
Acute disseminated staphylococcal disease (ADSD) constitutes a potentially fatal and alarmingly increasing disorder. We describe an unusual case of a two-and-a-half-year-old female with community-acquired methicillin-resistant Staphylococcus aureus induced septic shock complicated by osteomyelitis and deep vein thrombosis. Aggressive management with long-term antistaphylococcal therapy, anticoagulation and intensive care support was implemented with complete resolution of disseminated inflammation.
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