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[Ischemic stroke with sinus rhythm in patients with arterial hypertension]

G I Storozhakov, G E Gendlin, O V Uskova

    Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
    |April 25, 2013
    PubMed

    Insights

    Patients with acute ischemic stroke and hypertension showed increased left ventricular hypertrophy and diastolic dysfunction. Decreased blood flow velocity in the right auricle predicted cerebral vascular complications and outcomes.

    Area of Science:

    • Cardiology
    • Neurology
    • Hypertension Research

    Background:

    • Arterial hypertension is a major risk factor for cardiovascular and cerebrovascular diseases.
    • Left ventricular hypertrophy (LVH) and diastolic dysfunction are common in hypertensive patients.
    • The impact of these cardiac changes on acute ischemic stroke outcomes requires further elucidation.

    Purpose of the Study:

    • To investigate cardiac structural and functional changes in hypertensive patients during acute ischemic stroke.
    • To compare these changes with those in hypertensive patients without stroke complications.
    • To assess the predictive value of specific echocardiographic parameters for cerebrovascular complications and mortality.

    Main Methods:

    • Retrospective analysis of 71 hypertensive patients with acute ischemic stroke and sinus rhythm.
    • Comparison with 36 hypertensive patients without complications.
    • Inclusion of 91 previously examined hypertensive patients (3-8 years prior) using the same protocol.
    • Echocardiographic assessment including left ventricular hypertrophy, diastolic dysfunction, and right atrial blood flow.

    Main Results:

    • Patients with acute ischemic stroke exhibited greater left ventricular hypertrophy.
    • Signs of diastolic dysfunction were observed in both ventricles of stroke patients.
    • A statistically significant decrease in blood flow through the right auricle was noted in stroke patients.
    • Retrospective analysis indicated that decreased peak transmitral diastolic flow velocity (Ve) predicted cerebral vascular complications and lethal outcomes.

    Conclusions:

    • Hypertensive patients experiencing acute ischemic stroke present with distinct cardiac alterations, including LVH and diastolic dysfunction.
    • Reduced right atrial blood flow is associated with acute cerebral events in hypertension.
    • Transmitral diastolic flow velocity (Ve) may serve as a predictor for adverse cerebrovascular events and mortality in hypertensive individuals.

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