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Methylation metabolites in amniotic fluid depend on gestational age

Apolline Imbard1, Henk J Blom, Dimitri Schlemmer

  • 1Biochemistry Hormonology Laboratory, AP-HP Hôpital Robert Debré, Paris, France. apolline.imbard@rdb.aphp.fr

Prenatal Diagnosis
|April 25, 2013
PubMed
Summary

Amniotic fluid analysis reveals key methylation metabolite changes during pregnancy. Methionine decreases, while the S-adenosyl-L-methionine/S-adenosyl-L-homocysteine ratio increases, indicating growing fetal methylation capacity.

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