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Updated: May 12, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
A survey on selection and administration of perioperative antibiotics by anaesthetists
O T Alagbe-Briggs1, B O Onajin Obembe
1Department of Anaesthesiology, University of Port Harcourt Teaching Hospital, PMB 6173 Port Harcourt-Nigeria.
Background:
Perioperative antibiotic administration for prophylaxis of surgical site infections can increase the anaesthetists workload. However, timely administration is essential to reduce risks and improve patient outcome.
Objective:
This survey evaluates anaesthetists' opinion concerning perioperative antibiotic therapy and training.
Methodology:
Structured questionnaires relating to the study objective were administered to a cross-section of anaesthetists present at a national conference. The 16 question survey focused on the grade of anaesthetists, practice centre, opinion about perioperative antibiotic therapy and anaesthetists' training regarding use. Data was analysed and presented as percentages of total responses.
Results:
A total of 82 questionnaires were administered with 66 respondents (response rate- 81.0%); which included consultants 16(24.2%), residents 39(59.1%) and nurses 9(13.6%). Most 58(87.9%) were practicing in teaching hospitals and 62(93.9%) agreed that the surgeon was responsible for preoperative antibiotic selection. The anaesthetist 30(45.5%) and surgeon 26(39.4%) were responsible for preoperative administration, but the anaesthetist assumes responsibility following preoperative omissions 43(65.2%). Confirmation of administration pre-incision was by anaesthetist 31(47.0%) and surgeon 29(43.9%), but repeat administration during prolonged surgery was by former 38(57.6%). Training of anaesthetists in the selection 46(69.7%) and administration 36 (antibiotics was inadequate; and deemed necessary by 50(75.8%) and 55(83.3%) respondents respectively.
Conclusion:
Antibiotic selection though exclusively by the surgeon, higher responsibility is placed on the anaesthetist for preoperative administration, confirmation before incision and intraoperative re-dosing during prolonged surgery. Knowledge in selection and administration of antibiotics is inadequate and should be incorporated during the training.
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