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Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...

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Related Experiment Video

Updated: May 12, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

China interventional stroke registry: rationale and study design.

Xinfeng Liu1, Yunyun Xiong, Zhiming Zhou

  • 1Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China. xfliu2@yahoo.com.cn

Cerebrovascular Diseases (Basel, Switzerland)
|April 26, 2013
PubMed
Summary

The China Interventional Stroke Registry (CISR) is China's largest database for angioplasty and stenting in cerebral large artery stenosis. It tracks patient data, complications, and outcomes to assess real-world treatment adherence.

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Last Updated: May 12, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Area of Science:

  • Neurology
  • Interventional Cardiology
  • Public Health

Background:

  • Cerebral large artery stenosis treatment with angioplasty and stenting is increasing in China.
  • Limited data exists on the safety and long-term outcomes of these procedures in Chinese patients.
  • The China Interventional Stroke Registry (CISR) was established to address this knowledge gap.

Purpose of the Study:

  • To establish a comprehensive registry for cerebral interventional procedures in China.
  • To describe patient characteristics, procedural details, and clinical outcomes.
  • To evaluate adherence to guideline-based treatments in a real-world setting.

Main Methods:

  • Six medical centers contributed data to an internet-based registry since 2004.
  • Data collected includes demographics, clinical history, and angiography for patients undergoing angioplasty with/without stenting.
  • The registry covers both extracranial and intracranial arteries.

Main Results:

  • As of October 2012, data from 1,356 patients were collected.
  • The average patient age was 63.6 ± 10.2 years, with 79.9% being male.
  • Data quality was maintained through monthly feedback reports and quarterly monitoring meetings.

Conclusions:

  • The CISR is the first and largest registry of its kind in China.
  • It provides valuable insights into the characteristics and outcomes of patients undergoing angioplasty and stenting.
  • The registry will help understand real-world treatment adherence to guidelines in China.