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Related Concept Videos

Depressants01:28

Depressants

Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Carboxylic Acids to Primary Alcohols: Hydride Reduction01:17

Carboxylic Acids to Primary Alcohols: Hydride Reduction

Carboxylic acids, upon reaction with strong reducing agents such as lithium aluminum hydride followed by hydrolysis, undergo reduction to form primary alcohols.
Conversion of Alcohols to Alkyl Halides02:48

Conversion of Alcohols to Alkyl Halides

This lesson delves into the conversion of alcohols to corresponding alkyl halides and the mechanism of action for different reagents. Typically, the hydroxyl group is first protonated to convert it to a stable leaving group. Consequently, based on the starting alcohol, the mechanism undergoes either of the nucleophilic substitution routes, SN1 or SN2. Tertiary alkyl halides are made using the two-step SN1 mechanism that occurs via a carbocation intermediate, which is stabilized by...
Acid-Catalyzed Dehydration of Alcohols to Alkenes02:35

Acid-Catalyzed Dehydration of Alcohols to Alkenes

In a dehydration reaction, a hydroxyl group in an alcohol is eliminated along with the hydrogen from an adjacent carbon. Here, the products are an alkene and a molecule of water. Dehydration of alcohols is generally achieved by heating in the presence of an acid catalyst. While the dehydration of primary alcohols requires high temperatures and acid concentrations, secondary and tertiary alcohols can lose a water molecule under relatively mild conditions.
Aldehydes and Ketones with Alcohols: Hemiacetal Formation01:19

Aldehydes and Ketones with Alcohols: Hemiacetal Formation

Similar to water, alcohols can add to the carbonyl carbon of the aldehydes and ketones. The addition of one molecule of alcohol to the carbonyl compound forms the hemiacetal or half acetal. As depicted below, in a hemiacetal, the carbon is directly linked to an OH and OR group.

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Related Experiment Video

Updated: May 12, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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Published on: June 23, 2023

Alcoholic drinks as triggers in primary headaches.

Alessandro Panconesi1, Michela Franchini, Maria Letizia Bartolozzi

  • 1Headache Centre, Department of Neurology, San Giuseppe Hospital, Empoli, FI, Italy. a.panconesi@virgilio.it

Pain Medicine (Malden, Mass.)
|April 26, 2013
PubMed
Summary

Alcoholic drinks trigger headaches in a small fraction of migraine patients, but not migraine with aura or tension-type headaches. Many migraine patients are abstainers, with some avoiding alcohol due to headache concerns.

Keywords:
AlcoholAlcohol ConsumptionMigraineTension-Type HeadacheTrigger Factors

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Published on: June 2, 2014

Area of Science:

  • Neurology
  • Clinical Medicine

Background:

  • Alcoholic drinks (ADs) are frequently anecdotally reported as headache triggers.
  • The specific role of ADs in primary headache disorders requires further investigation.

Purpose of the Study:

  • To investigate the role of alcoholic drinks (ADs) as triggers for primary headaches, including migraine without aura, migraine with aura (MA), chronic migraine (CM), and tension-type headache (TH).

Main Methods:

  • Patients diagnosed with primary headache disorders were surveyed about AD consumption and headache precipitation.
  • Alcohol habits and individual characteristics were analyzed using binary logistic models.

Main Results:

  • Only 4.9% of patients, all with migraine, reported ADs as a trigger. No patients with MA or TH reported ADs as triggers.
  • Among migraine patients who consume ADs, only 8% identified them as a precipitating factor.
  • Occasional and habitual AD consumption was not associated with TH. Occasional drinkers had a lower risk of CM compared to abstainers.

Conclusions:

  • ADs trigger headaches in a small minority of migraine patients and do not appear to trigger MA or TH attacks.
  • The prevalence of abstainers among the study participants was higher than in the general population.