Related Experiment Video
Updated: May 12, 2026

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
Published on: November 29, 2015
Perioperative visual loss and anesthetic management
1Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington, USA. lorlee@uw.edu
Perioperative visual loss (POVL) is a rare complication of surgery. Modifying extrinsic risk factors may reduce the incidence of ischemic optic neuropathy in prone spinal fusion patients.
Area of Science:
- Anesthesiology
- Ophthalmology
- Neurosurgery
Background:
- Perioperative visual loss (POVL) is an infrequent but serious complication impacting patient quality of life.
- Cardiac, spine, and head and neck surgeries are most commonly associated with POVL.
- Recent large-scale studies have identified specific risk factors for POVL, particularly in prone spinal fusion procedures.
Purpose of the Study:
- To review findings from the largest multicenter case-control study on POVL.
- To summarize updated American Society of Anesthesiologists practice guidelines for POVL.
- To provide guidance on identifying and managing patients at high risk for POVL during prone spine surgery.
Main Methods:
- Review of a large multicenter case-control study on POVL.
- Analysis of epidemiology data from national databases.
- Discussion of POVL in robotic surgery and posterior reversible encephalopathy syndrome.
Main Results:
- Key risk factors for POVL in prone spinal fusion include male sex, obesity, Wilson spinal frame use, prolonged anesthesia, significant blood loss, and low colloid administration.
- These factors are associated with ischemic optic neuropathy.
Conclusions:
- Modifying patient-extrinsic risk factors may lower the incidence of ischemic optic neuropathy in prone spinal fusion.
- Further research is necessary to confirm the efficacy of these preventative strategies.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Aneurysm IV: Nursing Management
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Stages of General Anesthesia
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

