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Insomnia in patients with advanced cancer
Mellar P Davis1, Dilara Khoshknabi, Declan Walsh
11Department of Solid Tumor Oncology, Cleveland Clinic Taussig Cancer Center, Cleveland, OH, USA.
Introduction:
Insomnia is underrecognized in patients with cancer. By identifying clinical correlations and predisposing factors of insomnia, interventions may be initiated to treat insomnia.
Methods:
Consecutive patients referred to palliative medicine services were screened with a single question. Patients answering affirmatively completed the Insomnia Severity Index (ISI). Patients were screened for depression, fatigue, and pain. Spearman correlation was performed for associations.
Results:
Of 715 consecutive patients, 102 had sleep problems and 64 had clinical insomnia by the ISI criteria. Insomnia correlated with depression (r = .32), pain (r = .29), and tiredness (r = .40) but not with age or precipitating factors.
Discussion:
Insomnia severity moderately correlates with depression, pain, and tiredness. We found no association of insomnia severity with age or medications.
Conclusion:
Insomnia, pain, depression, and tiredness are a symptom cluster.
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