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Intra-partum fever and cerebral palsy in Khartoum, Sudan

Hala Abdullahi1, Mohamed Satti, Duria A Rayis

  • 1Department of Obstetrics and Gynecology, University of Khartoum, Khartoum, Sudan.

BMC Research Notes
|April 27, 2013
PubMed

Insights

Maternal fever during labor and poor infant sucking are significant predictors of childhood cerebral palsy (CP). These findings highlight key risk factors for CP, emphasizing the need for improved labor management to prevent this disability.

Area of Science:

  • Pediatrics
  • Neurology
  • Public Health

Background:

  • Cerebral palsy (CP) is a leading cause of childhood disability globally.
  • Predictors of CP vary significantly across different populations.
  • Understanding local risk factors is crucial for targeted prevention strategies.

Purpose of the Study:

  • To identify maternal and neonatal predictors of cerebral palsy (CP) in Khartoum, Sudan.
  • To investigate the association between maternal sociodemographic factors and neonatal outcomes with CP development.
  • To inform local public health initiatives for CP prevention.

Main Methods:

  • A case-control study was conducted involving 111 children with CP and 222 healthy controls.
  • Data on maternal characteristics and neonatal factors were collected using questionnaires.
  • Logistic regression analysis was employed to determine significant predictors of CP.

Main Results:

  • Maternal fever (OR=8.4), previous neonatal death (OR=5.4), and poor infant sucking (OR=30.5) were identified as significant predictors of CP.
  • Spastic CP constituted the majority (69.4%) of cases.
  • Maternal age, parity, birth weight, and sex were not found to be associated with CP in this cohort.

Conclusions:

  • Maternal fever during labor is a critical risk factor for developing cerebral palsy.
  • Poor neonatal sucking ability is a strong predictor of CP.
  • Enhanced labor management strategies are essential for CP prevention in this region.
Abstract

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