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Updated: May 12, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
Bleeding diatheses and preoperative screening
Edward A McGillicuddy1, Mark W Maxfield, Bernard Salameh
1Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06520-8062, USA. edward.mcgillicuddy@yale.edu
Insights
Perioperative bleeding risks require understanding coagulation. Surgeons must screen patients for bleeding disorders by reviewing medical history, medications, and using lab tests judiciously.
Area of Science:
- Hematology
- Surgical Medicine
Background:
- Bleeding disorders present significant risks during the perioperative period.
- A thorough understanding of the cell-based coagulation model is essential for surgical teams.
Purpose of the Study:
- To emphasize the importance of comprehensive screening for bleeding diatheses in surgical patients.
- To guide surgeons and consultants in managing perioperative bleeding risks.
Main Methods:
- Performing a detailed patient history and physical examination.
- Inquiring about all prescribed medications, nonprescribed supplements, and herbal preparations.
- Utilizing screening laboratory coagulation assays judiciously based on clinical context.
Main Results:
- Patient history and medication review are critical for identifying potential bleeding risks.
- Laboratory assays should complement clinical assessment, not replace it.
- Judicious use of coagulation tests improves perioperative safety.
Conclusions:
- Effective management of perioperative bleeding relies on a multi-faceted screening approach.
- Integrating clinical assessment with appropriate laboratory testing is key to mitigating bleeding risks.
- Surgeons must be knowledgeable about coagulation to ensure patient safety.
Abstract:
Bleeding disorders pose a significant perioperative risk. Surgeons and surgical consultants should have a working knowledge of the cell-based coagulation model. Careful screening for bleeding diatheses begins with a careful history and physical examination. It is paramount to ascertain what medications and nonprescribed supplements and herbal preparations a patient is taking, as these medications can have significant effects on perioperative bleeding tendencies. Finally, screening laboratory-based coagulation assays are available. These must be used judiciously with regard to a patient's history and the clinical circumstances surrounding the surgical stressor.
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