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Growth curves of preschool children in the northeast of iran: a population based study using quantile regression
Abolfazl Payande1, Hamed Tabesh, Mohammad Taghi Shakeri
1Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Insights
This study developed new weight-for-age growth charts for Iranian children aged 0-5 years. Local charts are essential as Iranian children’s growth patterns differ from international references, identifying at-risk populations.
Area of Science:
- Pediatrics
- Public Health
- Biostatistics
Background:
- Growth charts are vital for monitoring child development and identifying growth deviations.
- Existing international growth references may not accurately reflect the growth patterns of specific regional populations.
- Assessing children's growth status requires accurate and applicable methodologies.
Purpose of the Study:
- To construct localized weight-for-age growth charts and normal values for children aged 0 to 5 years in Northeast Iran.
- To compare the derived growth charts with World Health Organization (WHO) references and the LMS method.
- To evaluate the applicability of quantile regression for estimating growth curves.
Main Methods:
- A large cohort of 70,737 apparently healthy children (0-5 years) was surveyed.
- Anthropometric measurements were collected using standardized WHO methodology.
- Nonparametric quantile regression with local constant kernel estimation was employed.
Main Results:
- Weight-for-age growth curves were generated for boys and girls aged 0-5 years in Northeast Iran.
- Median weight values for Iranian children were lower than WHO reference data across all age groups.
- Boys exhibited higher weight curves than girls in all age categories.
Conclusions:
- Growth patterns in Northeast Iranian children differ significantly from international standards, necessitating local growth charts.
- International references may fail to identify growth issues in Iranian children.
- Quantile regression offers a flexible and robust method for establishing regional growth references.
Introduction:
Growth charts are widely used to assess children's growth status and can provide a trajectory of growth during early important months of life. The objectives of this study are going to construct growth charts and normal values of weight-for-age for children aged 0 to 5 years using a powerful and applicable methodology. The results compare with the World Health Organization (WHO) references and semi-parametric LMS method of Cole and Green.
Methods:
A total of 70737 apparently healthy boys and girls aged 0 to 5 years were recruited in July 2004 for 20 days from those attending community clinics for routine health checks as a part of a national survey. Anthropometric measurements were done by trained health staff using WHO methodology. The nonparametric quantile regression method obtained by local constant kernel estimation of conditional quantiles curves using for estimation of curves and normal values.
Results:
The weight-for-age growth curves for boys and girls aged from 0 to 5 years were derived utilizing a population of children living in the northeast of Iran. The results were similar to the ones obtained by the semi-parametric LMS method in the same data. Among all age groups from 0 to 5 years, the median values of children's weight living in the northeast of Iran were lower than the corresponding values in WHO reference data. The weight curves of boys were higher than those of girls in all age groups.
Conclusion:
The differences between growth patterns of children living in the northeast of Iran versus international ones necessitate using local and regional growth charts. International normal values may not properly recognize the populations at risk for growth problems in Iranian children. Quantile regression (QR) as a flexible method which doesn't require restricted assumptions, proposed for estimation reference curves and normal values.
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