Related Experiment Video
Updated: May 12, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Prospective outcome assessment of occupational rhinitis after removal from exposure
Roberto Castano1, Carole Trudeau, Lucero Castellanos
1Department of Surgery/Otolaryngology, Hôpital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada. roberto.castano@umontreal.ca
Objective:
To conduct a prospective evaluation of clinical and quality of life (QOL) outcomes of occupational rhinitis (OR) after cessation of exposure.
Methods:
We assessed changes in nasal symptoms, disease-specific QOL, nasal patency, and nasal inflammation in 20 subjects with confirmed OR. Olfactory function was assessed cross-sectionally at follow-up.
Results:
At follow-up, a significant decrease in the number of nasal symptoms and a significant improvement in QOL were observed. There were no significant differences in nasal patency outcomes. A not significant decrease in neutrophils number in nasal fluid and a significant decrease in macrophages were observed. As a group, study subjects showed a mild olfactory dysfunction at follow-up.
Conclusions:
We showed that cessation of exposure to causal agent improved QOL in patients with OR, leading to relief of rhinitis-associated symptoms and improvement in well-being.
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