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Published on: February 7, 2013
Staphylococcus aureus: determinants of human carriage
J U E Sollid1, A S Furberg2, A M Hanssen1
1Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Summary
Staphylococcus aureus colonization varies by location, age, and gender. This review examines factors influencing S. aureus carriage across different body sites and populations.
Area of Science:
- Microbiology
- Epidemiology
- Human Health
Background:
- Staphylococcus aureus is a common bacterium found on human skin and in mucous membranes.
- Carriage rates and locations of S. aureus vary significantly among individuals and populations.
- Understanding carriage dynamics is crucial for controlling S. aureus infections.
Purpose of the Study:
- To review observational studies on Staphylococcus aureus carriage.
- To explore the influence of bacterial, host, and environmental factors on S. aureus colonization.
- To identify key determinants of S. aureus carriage across different body sites.
Main Methods:
- Systematic review of observational studies on S. aureus carriage.
- Analysis of data on geographic location, age, gender, ethnicity, and body niche.
- Evaluation of bacterial, host, and environmental factors impacting colonization.
Main Results:
- The nares, throat, and perineum are the most common sites for S. aureus carriage in adults.
- Skin and intestinal colonization are also frequently observed.
- Carriage is influenced by a complex interplay of bacterial, host, and environmental factors.
Conclusions:
- Staphylococcus aureus colonization is multifactorial, influenced by diverse elements.
- Geographic, demographic, and environmental factors play a significant role in S. aureus carriage.
- Further research into these factors can inform strategies to manage S. aureus colonization and infection.
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