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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Updated: May 11, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

[Blood transfusions: risks beyond communicable diseases].

C Horn1, N Büser, A von Freyburg

  • 1Abteilung für Unfallchirurgie und Orthopädie, Klinikum Dachau. carsten.horn@gmx.com

Zeitschrift Fur Orthopadie Und Unfallchirurgie
|April 27, 2013
PubMed
Summary
This summary is machine-generated.

Blood transfusions in orthopaedic surgery are increasingly restricted due to improved techniques and understanding of anaemia. Evidence shows transfusions significantly impact patient mortality and outcomes, necessitating a review of current practices.

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Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
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Published on: January 2, 2013

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Last Updated: May 11, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
11:31

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols

Published on: January 2, 2013

Area of Science:

  • Orthopaedic Surgery
  • Transfusion Medicine
  • Patient Outcomes

Background:

  • Blood transfusions are routine in orthopaedic surgery and traumatology.
  • Evolving surgical techniques and understanding of anaemia pathophysiology are leading to stricter transfusion indications.
  • Growing evidence highlights the significant impact of blood transfusions on hospital mortality and patient outcomes.

Purpose of the Study:

  • To provide a comprehensive overview of recent literature on blood transfusions in orthopaedic surgery and traumatology.
  • To discuss the evolving indications for blood transfusion in the context of patient safety and outcomes.
  • To synthesize current evidence regarding the impact of blood transfusions on mortality and patient recovery.

Main Methods:

  • Literature review of recent studies.
  • Analysis of evidence on transfusion impact on mortality and patient outcomes.
  • Synthesis of data on changing transfusion guidelines in orthopaedics.

Main Results:

  • Recent literature indicates a trend towards more restrictive transfusion protocols.
  • Blood transfusions are associated with significant effects on hospital mortality.
  • Patient outcomes are demonstrably influenced by transfusion practices.

Conclusions:

  • Stricter transfusion guidelines are warranted in orthopaedic surgery and traumatology.
  • Minimizing unnecessary blood transfusions can improve patient outcomes and reduce mortality.
  • Further research and adherence to evidence-based practices are crucial for optimizing transfusion strategies.