Cancer chromosomes going to POT1
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Updated: May 11, 2026

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1Department of Laboratory Medicine and Pathology at Yale University School of Medicine, New Haven, Connecticut, USA. s.chang@yale.edu
Abstract:
Alterations in the single-stranded telomere-binding protein POT1 have recently been identified in chronic lymphocytic leukemia. This discovery provides novel insights into how genomic instability induced by dysfunctional telomeres contributes to tumorigenesis.
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