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Selective cavitand-mediated endocytosis of targeted imaging agents into live cells

Yoo-Jin Ghang1, Michael P Schramm, Fan Zhang

  • 1Department of Chemistry, School of Medicine, University of California, Riverside, California 92521, USA.

Journal of the American Chemical Society
|April 30, 2013
PubMed

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Receptor-mediated Endocytosis01:38

Receptor-mediated Endocytosis

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Receptor-mediated Endocytosis

Receptor-mediated endocytosis is when bulk amounts of specific molecules are imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle.
Clathrin-Mediated Endocytosis of LDL
One well-characterized example of receptor-mediated endocytosis is the...