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Related Experiment Video

Updated: May 11, 2026

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
16:23

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Published on: February 26, 2014

[Genetics of mouse-hole].

Bertrand Jordan1

  • 1CoReBio PACA, case 901, parc Scientifique de Luminy, 13288 Marseille Cedex 9, France. bertrand.jordan@univ-amu.fr

Medecine Sciences : M/S
|April 30, 2013
PubMed
Summary

Mouse burrowing behavior differences are innate. Genetic mapping reveals this complex behavior is controlled by a few genes, showing modular evolution.

Area of Science:

  • Ethology
  • Behavioral Genetics
  • Evolutionary Biology

Context:

  • The Oldfield mouse (Peromyscus polionotus) and Deer mouse (Peromyscus maniculatus) exhibit distinct burrowing architectures.
  • These behavioral differences are observed in both natural and laboratory settings, suggesting a strong innate component.

Purpose:

  • To genetically map the behavioral differences in burrow architecture between Oldfield mice and Deer mice.
  • To investigate the genetic basis of innate behaviors and understand the mechanisms of behavioral evolution.

Summary:

  • Researchers utilized new generation sequencing for genetic mapping to identify the genetic loci controlling burrowing behavior.
  • The study successfully mapped complex burrow architecture to a small number of genetic loci.
  • Evidence for modular evolution of behavior was demonstrated through these findings.

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Related Experiment Videos

Last Updated: May 11, 2026

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Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Published on: February 26, 2014

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Impact:

  • Provides insights into the genetic underpinnings of complex innate behaviors.
  • Highlights the role of specific genes in shaping distinct behavioral phenotypes.
  • Offers a framework for studying the modularity and evolution of behavior in other species.