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Related Concept Videos

Alterations in Muscle Tone ll01:12

Alterations in Muscle Tone ll

Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
Visual Agnosia01:12

Visual Agnosia

Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round end"...
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Dementia

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Updated: May 11, 2026

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
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Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Published on: October 13, 2016

Ataxia.

Sara Winchester1, Piyush K Singh, Mohamad A Mikati

  • 1Division of Pediatric Neurology, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.

Handbook of Clinical Neurology
|April 30, 2013
PubMed
Summary
This summary is machine-generated.

Diagnosing childhood ataxia involves a thorough history, neurological exam, blood tests, brain imaging, and genetic testing. This comprehensive approach helps differentiate various causes, from intoxication to rare metabolic disorders.

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Area of Science:

  • Pediatric Neurology
  • Neurogenetics
  • Diagnostic Medicine

Background:

  • Childhood ataxia presents a diagnostic challenge due to its diverse etiologies.
  • Accurate diagnosis is crucial for timely and appropriate management.

Purpose of the Study:

  • To outline a systematic approach for diagnosing ataxia in children.
  • To provide a comprehensive differential diagnosis for acute and recurrent ataxia.

Main Methods:

  • Detailed patient history and comprehensive general and neurological examinations.
  • Selected blood work, brain imaging (MRI/CT), and genetic testing.
  • Consideration of various etiologies including intoxication, infections, vascular events, tumors, and metabolic disorders.

Main Results:

  • A broad spectrum of conditions can cause ataxia in children, ranging from common intoxications to rare inherited metabolic diseases.
  • Episodic and progressive presentations are characteristic of inherited ataxias.
  • A structured diagnostic pathway is essential.

Conclusions:

  • A multidisciplinary approach involving pediatric neurologists, geneticists, and therapists is vital for optimal patient care.
  • Early and accurate diagnosis facilitates targeted treatment and improves outcomes for children with ataxia.