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Published on: July 1, 2018
Postmortem diagnosis of sudden unexpected death from Streptococcus suis type 2 infection: a case report
Boonsak Hanterdsith1, Prasit Tharavichitkul, Pongsak Mahanupab
1Department of Emergency Medicine and Forensic Medicine, Maharaj Nakhonratsima Hospital, Thailand. trapezius60@yahoo.com
Abstract:
Streptococcus suis causes meningitis, septicemia, arthritis, endocarditis and death in both pigs and humans. Sudden death is rarely documented in the forensic field and almost all cases were diagnosed pre-mortem. Here we report a 49-year-old man who died from S. suis type 2 infection. S. suis was identified as the causative pathogen using bacterial culture, standard biochemical and coagglutination tests, specific DNA amplification by polymerase chain reaction, and histopathologic examination. We discuss the postmortem investigation of a suspected S. suis infection.
Insights
Sudden death in humans from Streptococcus suis type 2 infection is rare. This case highlights the importance of postmortem investigations for identifying this zoonotic pathogen.
Area of Science:
- Veterinary Medicine
- Human Medicine
- Infectious Diseases
Background:
- Streptococcus suis is a zoonotic pathogen causing severe illness in pigs and humans.
- Meningitis, septicemia, and endocarditis are common clinical manifestations.
- Sudden death due to S. suis is infrequently documented, especially in forensic contexts.
Observation:
- A 49-year-old male presented with sudden death.
- S. suis type 2 infection was identified as the cause of death.
- Diagnosis was confirmed through bacterial culture, biochemical tests, PCR, and histopathology.
Findings:
- This case represents a rare instance of pre-mortem diagnosis failure leading to sudden death.
- Comprehensive diagnostic methods confirmed S. suis type 2 as the causative agent.
- The study emphasizes the utility of molecular and histopathological techniques in postmortem S. suis identification.
Implications:
- Accurate postmortem diagnosis of S. suis is crucial for public health.
- Understanding S. suis pathogenesis aids in preventing zoonotic transmission.
- This case underscores the need for vigilance in diagnosing S. suis infections, even in unexpected presentations.
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