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Updated: May 11, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
Spray-on-skin cells in burns: a common practice with no agreed protocol
Ammar Allouni1, Remo Papini, Darren Lewis
1Burns and Plastic Department, Queen Elizabeth Hospital Birmingham, Birmingham, West Midlands B15 2TH, UK.
Objectives:
Cultured epithelial autograft (CEA) has been used for skin coverage after burn wound excision since 1981. It is used in burn units and centres throughout the U.K.; however, there appears to be no agreed standards of practice. We aimed to investigate the experience and current practice with its usage in the management of acute burn injury.
Methods:
An online survey was sent to twenty-five burns consultants in the U.K., who are members of the British Burn Association.
Results:
We received 14 responses. Rarely have the responders agreed to the same practice in most of the questions. Different choices were given by responders with regards the indications for cell culture, techniques used, primary and secondary dressings used, first wound review timing, and measures used to evaluate outcomes.
Conclusion:
In the current economic environment, the NHS needs to rationalize services on the basis of cost effectiveness. CEA is an expensive procedure that requires an adequately sterile laboratory, special equipments and highly experienced dedicated staff. When dealing with expensive management options, it is important to have an agreed protocol that can form the standard that can be referred to when auditing practices and results to improve burn management and patients' care.
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