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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
1:1 atrial-flutter. Prevalence and clinical characteristics
Béatrice Brembilla-Perrot1, Franck Laporte, Jean Marc Sellal
1Department of Cardiology, Nancy University Hospital, Rue du Morvan 54511 Vandoeuvre-les-Nancy, France.
Insights
The prevalence of 1:1 atrial flutter (AFL) is 8% in patients undergoing ablation. These patients are younger, have less heart disease, and more atrial fibrillation history, but share similar prognoses.
Area of Science:
- Cardiology
- Electrophysiology
- Epidemiology
Background:
- Epidemiology of 1:1 atrial flutter (AFL) is not well-understood.
- Identifying predisposing conditions for 1:1 AFL is crucial for patient management.
Purpose of the Study:
- To determine the prevalence of 1:1 AFL in patients referred for ablation.
- To identify factors predisposing to 1:1 AFL.
Main Methods:
- A consecutive cohort of 1037 patients undergoing AFL ablation was analyzed.
- Patients were followed for an average of 3 years post-ablation.
Main Results:
- The prevalence of 1:1 AFL was 8%, with these patients being younger and having less heart disease.
- Absence of heart disease, history of atrial fibrillation, and use of Class I antiarrhythmics were associated with 1:1 AFL.
- Prognosis, including ablation failure, complications, and subsequent atrial fibrillation, was similar between groups.
Conclusions:
- 1:1 AFL occurs in 8% of patients undergoing ablation.
- Younger age, less heart disease, prior atrial fibrillation, and Class I antiarrhythmic use are linked to 1:1 AFL.
- The long-term prognosis for patients with 1:1 AFL is comparable to those without.
Unlabelled:
Little is known about the epidemiology of 1:1 atrial flutter (AFL). Our objectives were to determine its prevalence and predisposing conditions.
Methods:
1037 patients aged 16 to 93 years (mean 64±12) were consecutively referred for AFL ablation. 791 had heart disease (HD). Patients admitted with 1/1 AFL were collected. Patients were followed 3±3 years.
Results:
1:1 AFL-related tachycardiomyopathy was found in 85 patients, 59 men (69%) with a mean age of 59±12 years. The prevalence was 8%. They were compared to 952 patients, 741 men (78%, 0.04), with a mean age of 65±12 years (0.002) without 1:1 AFL. Factors favoring 1:1 AFL was the absence of HD (35 vs 23%, 0.006), the history of AF (42 vs 30.5%)(0.025) and the use of class I antiarrhythmic drugs (34 vs 13%)(p<0.0001), while use of amiodarone or beta blockers was less frequent in patients with 1:1 AFL (5, 3.5%) than in patients without 1:1 AFL (25, 15%) (p<0.0001, 0.03). The failure of ablation (9.4 vs 11%), ablation-related complications (2.3 vs 1.4%), risk of subsequent atrial fibrillation (AF) (20 vs 24%), risk of AFL recurrences (19 vs 13%) and risk of cardiac death (5 vs 6%) were similar in patients with and without 1:1 AFL.
Conclusions:
The prevalence of 1:1 AFL in patients admitted for AFL ablation was 8%. These patients were younger, had less frequent HD, had more frequent history of AF and received more frequently class I antiarrhythmic drugs than patients without 1:1 AFL. Their prognosis was similar to patients without 1:1 AFL.
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