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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
["En face" optical coherence tomography for multiple evanescent white dot syndrome]
F Combillet1, M-B Rougier, M Blaizeau
1Unité rétine, uvéite et neuro-ophtalmologie, service d'ophtalmologie, CHU de Bordeaux, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
Journal Francais D'Ophtalmologie
|April 30, 2013
Summary
Multiple evanescent white dot syndrome (MEWDS) involves retinal lesions. Advanced "en face" optical coherence tomography (OCT) visualized these lesions, matching findings from indocyanine green angiography (ICGA).
Area of Science:
- Ophthalmology
- Retinal Imaging
- Neuroscience
Background:
- Multiple evanescent white dot syndrome (MEWDS) is a rare retinal disorder causing temporary vision loss.
- The underlying cause of MEWDS is not fully understood.
- This study aimed to pinpoint MEWDS lesion locations within the neurosensory retina.
Observation:
- A patient with MEWDS underwent advanced "en face" optical coherence tomography (OCT) and angiography.
- "En face" OCT provided detailed reconstructions of retinal layers and the inner choroid.
- Fluorescein angiography and indocyanine green angiography (ICGA) were also performed.
Findings:
- "En face" OCT revealed signal attenuation in the IS/OS photoreceptor junction and inner choroid during the acute phase of MEWDS.
- These areas of attenuation formed a distinct spot pattern.
- This pattern precisely matched the hypofluorescent dots observed with ICGA.
Implications:
- "En face" OCT is a novel, noninvasive tool for visualizing MEWDS.
- The technology can identify specific attenuation patterns at the IS/OS junction.
- These findings correlate directly with ICGA results, aiding in MEWDS diagnosis and understanding.
Keywords:
Advanced “en face” visualization modeAngiographie au vert d’infracyanineInflammationInfracyanine green angiographyMultiple evanescent white dot syndromePhotoreceptorsPhotorécepteursSyndrome des taches blanches évanescentes multiplesTomographie par cohérence optique « en face »“En face” optical coherence tomography
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