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Related Experiment Video

Updated: May 11, 2026

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

Same-day discharge after percutaneous coronary intervention: a meta-analysis.

Kimberly M Brayton¹, Vishal G Patel, Christopher Stave

¹Center for Primary Care & Outcomes Research, Stanford School of Medicine, Stanford University, Stanford, CA, USA. kbrayton@stanford.edu

Journal of the American College of Cardiology

|April 30, 2013

Summary

Same-day discharge after percutaneous coronary intervention (PCI) is safe for selected patients. This meta-analysis found low complication rates, comparable to overnight observation, for elective PCI procedures.

Keywords:

ACS CAD MI PCI RCT TLR acute coronary syndrome coronary artery disease myocardial infarction percutaneous coronary intervention randomized controlled trial same-day discharge target lesion revascularization

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Last Updated: May 11, 2026

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

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Published on: December 16, 2022

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Area of Science:

Cardiology
Interventional Cardiology
Health Services Research

Background:

Previous evaluations of same-day discharge after PCI were limited to small, single-center studies.
The safety and efficacy of early discharge protocols require robust evidence from larger, diverse patient populations.

Purpose of the Study:

To assess the safety and efficacy of same-day discharge following percutaneous coronary intervention (PCI).
To compare outcomes of same-day discharge versus routine overnight observation in PCI patients.

Main Methods:

A meta-analysis was conducted on 37 studies, including 7 randomized controlled trials (RCTs) and 30 observational studies, encompassing 12,803 patients.
Data collected included demographics, procedural details, and adverse events, focusing on composite outcomes of death, myocardial infarction (MI), target lesion revascularization (TLR), major bleeding, and vascular complications.

Main Results:

In RCTs (n=2,738), same-day discharge showed no significant difference in death/MI/TLR (OR: 0.90; 95% CI: 0.43-1.87) or major bleeding/vascular complications (OR: 1.69; 95% CI: 0.84-3.40) compared to overnight observation.
Observational studies (n=10,065) reported low pooled rates for death/MI/TLR (1.00%) and major bleeding/vascular complications (0.68%).

Conclusions:

Same-day discharge appears to be a safe strategy for selected patients undergoing elective PCI.
The low rate of major complications supports same-day discharge as a viable alternative to routine overnight observation.