Related Experiment Video
Updated: May 11, 2026

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
Published on: July 5, 2024
Healing of normal and osteopenic bone with titanium implant and low-level laser therapy (GaAlAs): a histomorphometric
Luana Marotta Reis de Vasconcellos1, Mary Anne Moreira Barbara, Camila Porto Deco
1Department of Bioscience and Oral Diagnosis, São Jose dos Campos School of Dentistry, State University of São Paulo (UNESP), Av. Engenheiro Francisco José Longo, 777, São José dos Campos, 12245-000, São Paulo, Brazil.
Abstract:
The study investigates the influence of low-level laser therapy (LLLT) on bone healing in the femur of osteopenic and normal rats with titanium implants. Ovariectomy and control group were randomly submitted to LLLT, which was applied by gallium-aluminum-arsenium (GaAlAs) laser at the surgical site before and after placing the implant, for seven times. Histomorphometric and statistical analysis were performed. Most irradiated groups showed higher values than the nonirradiated groups. The GaAlAs infrared diode laser may improve the osseointegration process in osteopenic and normal bone, particularly based on its effects in the initial phase of bone formation.

