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Heart failure in China: a review of the literature
Rinat Ariely1, Keith Evans, Tim Mills
1GlaxoSmithKline, King of Prussia, PA, USA.
Insights
Heart failure (HF) prevalence in China is lower than in Western countries, with hypertension and coronary heart disease as leading causes. Physician knowledge of advanced HF treatments needs improvement, especially in rural areas.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Heart failure (HF) is a significant cause of hospitalization and mortality globally.
- Limited data exist on HF epidemiology, management, and quality of life in China.
- Understanding HF in China is crucial for improving patient outcomes.
Purpose of the Study:
- To review Chinese and English literature on HF causes, risks, treatment, and outcomes in China.
- To identify gaps in current knowledge and guide future research.
- To inform clinical practice and public health strategies for HF management in China.
Main Methods:
- Systematic literature review of Chinese and English publications.
- Inclusion of studies focusing on HF epidemiology, etiology, treatment, and health outcomes.
- Exclusion of studies from Taiwan and Hong Kong.
Main Results:
- HF prevalence in China appears lower than in Western countries.
- Hypertension and coronary heart disease are primary HF causes in China.
- Use of newer HF pharmacotherapies is increasing, but physician knowledge gaps persist, particularly in rural areas.
- Development of Chinese quality of life measures for HF is emerging.
Conclusions:
- Significant gaps remain in understanding HF in China.
- Further research is needed to establish a robust Chinese evidence base for HF management.
- Addressing physician knowledge deficits and improving access to advanced treatments are critical for enhancing HF care in China.
Abstract:
Heart failure (HF) is a serious disease associated with high morbidity and mortality. In China, as in other countries, it is a common cause for hospital admission; however, as yet there are few data documenting the epidemiology and management of HF in China, or quality of life-related considerations in this population. This review aims to identify relevant Chinese and English language publications that discuss the causes, risks, treatment, and health outcomes (costs, health-related quality of life) of HF in China (excluding Taiwan and Hong Kong). The prevalence of HF in China appears to be lower than that reported in many Western countries, including the US. Hypertension and coronary heart disease are the leading causes of HF in China, as they are in many Western nations, potentially highlighting the improvement in socioeconomic conditions in China. Evidence suggests that use of newer pharmacological agents for the treatment of HF is increasing; however, it is still believed that there is a lack of physician knowledge regarding newer, more effective treatment options, with rural (poor) areas appearing to be the most reliant on older, less expensive, medications. Interest in Chinese quality of life measures for HF has risen recently, with the development of valid and reliable rating scales in the Chinese population. Although the amount of available literature on HF in China is improving, there remain significant gaps in our understanding of the issue, and further research is needed to provide a reliable Chinese evidence base for the improvement of clinical practice.
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